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100ml ( Amoxicillin + Clavulanic acid ) bronchopneumonia, mastitis, metritis, parainfluenza, paratyphoid, pyelonephritis, umbilical infections, wound infections, wounds, swine rust, urethritis, cystitis, endometritis analog Clavamox ®, Synulox®

$83,90 $73,90

 

Description

 

COMPOSITION

1 ml of the product contains

active ingredients:

Amoxicillin
(in the form of Amoxicillin trihydrate) – 140 mg;

Clavulanic acid
(in the form of Potassium clavulanate) – 35 mg.

 

PHARMACOLOGICAL PROPERTIES

Amoxicillin is a semisynthetic antibiotic of the penicillin series. Its mechanism of action consists in disruption of the synthesis of the cell walls of the bacteria, inhibition of enzymes of transpeptidase and carboxypeptidase, disruption of osmotic balance, which leads to the death of the bacteria at the growth stage. Amoxicillin has a broad spectrum of action against Gram-positive and Gram-negative microorganisms such as: Staphylococcusspp., Streptococcus, spp. (S.agalactiae, S.dysgalactiae, S.uberis), E.coli, Arcanobacteria (including A.pyogenes), Corynebacteria spp, Clostridia spp, Bacillus anthracis, Actinomyces bovis, Bacillus cereus, Bacteroides (including strains producing β-lactamase), Campilobacter spp, Klebsiella spp, Pasteurella spp, Escherichia coli, Salmonella spp, Proteus spp, Fusobacterium necrophorum, Haemophilus spp, Moraxella spp, Actinobacillus lignieresi.

Clavulanic acid is one of the natural metabolites of Streptomyces clavuligerus. It has similarities with penicillin in its structurally similar core with a β-lactam ring. Clavulanic acid is an inhibitor of the β-lactamase enzyme, whose action is initially active and is eventually deactivated. Clavulanic acid penetrates the bacterial cell wall and binds external and intracellular β-lactamase enzymes.

Amoxicillin in combination with an inhibitor of this enzyme (clavulanic acid) broadens the spectrum of antimicrobial action.

After parenteral injection, the drug is quickly absorbed and distributed throughout the body tissues, reaching high concentrations in muscle tissues, liver, and kidneys.

 

TARGET ANIMALS

Cattle, steers, piglets, pigs, calves

 

INDICATIONS FOR USE

Treatment of cattle, pigs for diseases of the respiratory system (bronchitis, bronchopneumonia, rhinitis), the urogenital system (metritis, endometritis, cystitis, urethritis, pyelonephritis), joints, skin and soft tissue (belly infections, wounds, abscesses, inflammation), as well as treatment of animals with leptospirosis, mastitis, agalactia in pigs, actinomycosis, swine rye, parainfluenza and paratyphus caused by microorganisms sensitive to amoxicillin and clavulanic acid.

 

METHOD OF ADMINISTRATION AND DOSAGES

Intramuscularly – 1 ml of preparation per 44lb (20 kg) of body weight once daily during 3-5 days.

Shake the drug thoroughly before injection.
Only dry syringes and needles should be used for administration.
Wipe the cap with a napkin soaked in antiseptic solution before the set.
After injection, massage the injection site.

 

HATCHING PERIOD:

Slaughter of animals for meat is allowed 42 days after the last drug administration. Consumption of milk for human consumption shall be allowed 60 hours after the last drug administration.
Meat and milk obtained before the specified period shall be utilized or fed to unproductive animals, depending on the opinion of a veterinarian.

Shelf life. – 2 years.

After first withdrawal of preparation from vial: 28 days on condition of storage in dark place at temperature 40-77 F  ( 5 ° to 25 ° C ).

STORAGE CONDITIONS

In a dark place out of the reach of children at 40-77 F  ( 5° to 25°C ).

 

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