Description
Composition:
100 ml of the preparation contain
active ingredients:
Enrofloxacin – 10 grams;
Colistin sulfate – 100 000 000 IU;
Pharmacological action:
Enrocolin – a complex drug, the therapeutic effect of which is due to the synergistic effect of the active components of the drug: enrofloxacin and colistine sulfate. Enrofloxacin belongs to the group of fluoroquinolones of the second generation, it prevents the synthesis of DNA in the nuclei of microbial cells. The preparation contains bactericidal action against Gram-positive and Gram-negative microorganisms (Staphylococcus aureus, Enterobacteriaceae spp., Pasteurella spp.., Haemophilus spp., Actinobacillus spp., Brucella spp., Bordetella bronchiseptica, Pseudomonas aeruginosa, Salmonella spp., Pasteurella spp., etc.), and also against mycoplasma (Mycoplasma spp.) and chlamydia (Chlamydia spp.).
Colistin is an antibiotic of a group of polymixins, which is synthesized by the aerobic spore-forming bacillus polymyxa stick. The preparation has a bactericidal effect on Gram-negative bacteria (E. coli , Salmonella spp., Pasteurella spp., Haemophilus spp., Bordetella spp.). Colistin binds with phospholipids of cytoplasmic membrane, increases its permeability for both intra- and extracellular components, which leads to destruction of bacteria cells.
The drug is quickly absorbed and penetrates into all organs and tissues of the body. The maximum concentration of the drug in the blood is reached 2 hours after application. The therapeutic concentration is maintained for 24 hours.
It is excreted from the body with urine, bile and faeces.
Application:
Treatment of cattle, calves (up to 3 months), pigs and poultry with respiratory and gastrointestinal diseases caused by microorganisms sensitive to enrofloxacin and colistine.
Basic indications for use:
chronic respiratory diseases (Mycoplasma gallisepticum, E. Coli);
infectious synovitis (Mycoplasma synoviae);
Aerosaculites (M. meleagridis);
colibacilllosis (E. coli);
salmonella (Salmonella spp.);
pasteurellosis (Pasteurella multocida);
turkey bordelliosis (Bordetella avium);
face (Erysipelothrix rhusiopathiae);
Staphylococcus aureus;
chlamydia psittaci.
Dosage and administration
| ANIMAL VIEW AND CATEGORY | INDICATIONS | DOSAGE | APPOINTMENT DURATION | METHOD OF APPLICATION |
| Calves up to 3 months of age, pigs |
In diseases of bodies of breath and gastrointestinal tract |
0.3-0.5 ml / 2,2lb (1kg) body weight |
3-5 days | Orally in drinking water |
| Poultry (chickens, broilers, turkeys) |
With salmonellosis , mixed infections, with chronic forms of poultry diseases |
0.5-1.0 ml / l of water for evaporation |
5-7 days |
During treatment, the bird should receive only water containing the medicine. The treatment solution is prepared daily in the volume of water intended for poultry consumption during the day.
Removal period :
It is allowed to slaughter animals for meat 12 (calves and pigs) and 11 (poultry) days after the last application.
The meat received before the specified period is fed to unproductive animals or disposed of, depending on the opinion of the veterinary surgeon.
Shelf life – 2 years
After dilution with water, the preparation should be used within 24 hours.
Storage conditions:
Store in a dark, inaccessible place for children at temperatures between 40-77F (5 to 25 ° C).
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