22lb (1000grams Colistine sulfate + oxytetracycline hydrochloride + trimethoprim) for animals

Description

Powder of light yellow color, well soluble in water.

Composition:

1 gram of the preparation contains active ingredients:

colystine sulfate – 500 000 IU,

Oxytetracycline hydrochloride – 35 mg,

trimethoprim, 90 mg.

Pharmacological properties:

Ultrafom is a complex preparation, the components of which, acting synergistically, provide a wide range of antimicrobial action.
Oxitetracycline is a bacteriostatic antibiotic. The drug has a wide range of effects on Gram-positive and Gram-negative microorganisms: Streptococcus spp., Clostridium spp., Corynebacterium spp., Brucella spp., Haemophilus spp, E. coli, Pasteurella spp., Klebsiella spp., Erysipelothrix spp., Fusobacterium spp., Salmonella spp., as well as for naiprostis (Protozoa), mycoplasma spp., rickettsia (Rickettsia spp.) and chlamydia (Chlamydia). The mechanism of action of oxytetracycline consists in violation of the synthesis of protein in its interaction with ribosomes, as well as in reducing the permeability of the cytoplasmic membrane of sensitive microorganisms.

Colistin is an antibiotic from the group of polymixins and has a bactericidal effect on gram-negative microorganisms (e.g. E. soli, Salmonella spp., Pasteurella spp., Haemophilus spp., Bordetella spp.) The mechanism of action of colistin consists in violation of the integrity of the cytoplasmic membrane of microorganisms. Colistine interacts with phospholipids, destroying the structure of the cell membrane. Bacterial membrane permeability changes immediately after contact with the drug. Colistine binds phospholipid A to cell membranes, neutralizing the biological effect of bacterial endotoxin.

Trimethoprim is a chemotherapeutic drug with a bactericidal effect against gram-positive ones (Staphylococcus spp., Streptococcus spp., Clostridium spp., Corynebacterium spp. And others) and gram-negative (E. coli, Salmonella spp., Klebsiella spp., Proteus spp., Pasteurelia spp., Bordetella spp. etc.) microorganisms. It inhibits bacterial reductase, which converts dehydrofoliic acid into tetrahydrofoliic acid, which is essential for the synthesis of purines and nucleic acids. This trimethoprim blocks one of the main processes of bacterial metabolism in the pathway of protein synthesis.

Application:

Pigs: treatment of animals with dysentery, colibacillosis, pasteurellosis, salmonellosis, as well as diseases of the digestive tract and respiratory tract caused by microorganisms sensitive to oxytetracycline, colistine and trimethoprim.

Rabbits, calves and lambs (up to six weeks old): treatment of animals suffering from enteritis, as well as respiratory diseases caused by microorganisms sensitive to oxytetracycline, colistine and trimethoprim.

Poultry (chickens, turkeys, pheasants, geese, ducks): treatment of poultry, patients with mycoplasmosis, colibacillosis, pasteurelezoma, as well as diseases of the respiratory system caused by microorganisms sensitive to oxytetracycline, colistine and trimethoprim.

Dosage:

Oral in dose:

pigs, poultry (group method) – 0,22lb (1 kg) of the preparation per 1000 liters of drinking water, or 3,30-4.40 lb (1,5-2 kg) of the preparation per ton of mixed fodder within 3-5 days;

Rabbits – 1-1.5 grams of the preparation per liter of drinking water within 3-5 days;

calves and lambs (up to six weeks old), piglets (individually) – 0.5 g of the preparation per 22 lb (10 kg) 2 times a day for 5-7 days.

Contraindications:
Do not use the drug with hypersensitivity to the components of the drug. It is forbidden to use laying hens, eggs of which are used as food for people.

Warning:
Killing of animals and poultry for meat is allowed after 10 (calves, lambs, pigs, rabbits) and 7 (poultry) days after the last application of the drug. The meat is disposed of or fed to unproductive animals by the indicated deadline, depending on the opinion of the veterinary surgeon.

Storage
Dry, dark place at a temperature of 45-77F (8 ° to 25 ° C).
Shelf life – 3 years.