1000 grams ( Gentamicin sulfate + Sulfadimizin + Trimethoprim ) Calves, lambs, goats sick for pasteurellosis, mycoplasmosis, dysentery, salmonellosis, bronchopneumonia caused by microorganisms

$174,90 $158,90



Powder from white to gray in color with a specific smell of the components.



1 gram of the product
active substances:

Gentamicin sulfate – 40 mg;
Sulfadimizin – 100 mg;
Trimethoprim – 20 mg.




ATC vet classification code QJ01 – Veterinary antibacterial drugs for systemic use.

QJ01RA97 – Aminoglycosides, combination with other antimicrobials.

Gentazimvet ® is a combination drug consisting of gentamicin sulfate, sulfadimizin and trimethoprim. As a result of synergism of the active substances, the activity of the drug is significantly higher than that of its individual components.

Gentamicin is an aminoglycoside antibiotic. Its mechanism of action is to disrupt bacterial protein synthesis by binding to the 30S-subunit of bacterial ribosomes. Under these conditions a protein with a mismatched amino acid sequence is formed. It is active against Gram-negative and Gram-positive microorganisms: Escherichia coli, Salmonella spp, Enterobacter aerogenes, Klebsiella spp., Some species of Proteus spp. and Seuratia spp., Pseudomonas aeruginosa, Pasteurella multocida, Staphylococcus aureus, Serpulina hydeurea, Mycoplasma spp.

Sulfadimizine and trimethoprim act bacteriostatically against Gram-positive and Gram-negative microorganisms (Staphylococcus spp., Streptococcus spp., Clostridium spp., Listeria monocytogenes, Corynebacterium spp., E. coli, Salmonella spp., Klebsiella spp., Proteus spp., Pasteurella spp., Bordetella spp. and others).

Their mechanism of action is the sequential inhibition of enzymes involved in the synthesis of folic acid, thereby inhibiting the synthesis of thymidine of the bacterial cell. Sulfadimizine blocks the conversion of para-aminobenzoic acid to dihydrofolic acid, and trimethoprim blocks the conversion of dihydrofolic acid to tetrahydrofolic acid by inhibiting dihydrofolate reductase.

Gentamicin is poorly absorbed in the digestive tract. Approximately 30% of the antibiotic is bound to plasma proteins. Therapeutic concentration is retained in the body from 8 to 12 hours.

Gentamicin also penetrates into pleural and abdominal cavity and through the placenta. It is excreted in active form through the kidneys.

Sulfadimizine and trimethoprim are well distributed in the body after oral administration and penetrate through the placenta. In inflammation of the brain membranes, the concentration may reach 50% of the serum concentration.

Sulfadimizine and trimethoprim are excreted through the kidneys by glomerular filtration and tubular secretion. They are metabolized in the liver. Sulfadimizine is mainly acetylated and conjugated to glucuronic acid, trimethoprim is metabolized to oxide and hydroxyl metabolites.




Calves, lambs and goats up to 3 months of age: treatment of animals sick with pasteurellosis, mycoplasmosis, dysentery, salmonellosis, bronchopneumonia caused by microorganisms sensitive to components of the drug.

Pigs: treatment of animals with dysentery, pneumonia, MMA syndrome, rye, colibacillosis, salmonellosis, pasteurellosis caused by microorganisms sensitive to the drug components.

Poultry (broiler chickens, turkeys): treatment of poultry sick with salmonellosis, pasteurellosis and respiratory diseases caused by microorganisms sensitive to components of the drug.




Orally in doses:

– calves, lambs and goats up to 3 months of age – 1.0 gram of the drug per 22lb (10 kg) of animal body weight;

– pigs – 1.0 gram of the preparation per 22lb (10 kg) of body weight;

– poultry (broiler chickens, turkeys) – 1 gram per 5.5-6.0lb (2.5-2.8 kg) of feed, or 2.2lb (1 kg) per 2000 liters of drinking water.

Administered at intervals of 24 hours, treatment course 3-5 days.




Hypersensitivity to gentamicin, sulfadimizin and trimethoprim.
Do not use in animals with impaired renal function, liver and hearing and vestibular system disorders.
Do not use simultaneously with other aminoglycoside antibiotics and antibiotics with nephrotoxic effect (polymyxin B, colistin, amphotercin, chloramphenicol, cephalosporin, erythromycin), with muscle relaxants and anesthetic agents, heparin, B vitamins, diuretics (furosemide).
Do not use in laying hens whose eggs are used for human consumption as well as in ruminants with functionally developed pre-stomachs.




Slaughter of animals and poultry for meat shall be allowed 7 days after the last drug administration. Any meat obtained before the specified period shall be utilized or fed to non-productive animals depending on the opinion of a veterinarian.

Do not use simultaneously with preparations containing PABA as this reduces the antibacterial effect.




Store in a dry, dark place out of the reach of children at temperatures between 40 and 77 °F (5 ° C to 25 ° C).


Shelf life – 3 years


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