Description
1 pack = 100 ml
Drug for treatment and prevention of coccidiosis in dogs, young cattle and pigs
Dosage form: oral suspension.
Composition :
In 1 ml of the active
Ingredients:
1 ml of active substance contains:
Toltrazuril – 50 mg
Pharmacological properties :
Toltrazuril refers to anticoccidial drugs of triazintrione group.
Toltrazuril as part of the drug has a broad spectrum of coccidiocidal action at stages of intracellular development of parasites, effective against all types of coccidia, including Eimeria spp., Isospora spp., Cistoisospora spp. parasitizing in piglets, calves, lambs, rabbits, puppy dogs and fur-bearing animals.
Toltrazuril has damaging effect on mitochondria and division processes of coccidia nuclei, disrupting formation of macrogametocytes, blocking respiratory enzymes, causing death of parasites.
After oral administration the drug toltrazuril is slowly absorbed and has coccidiocidal effect on mucosa and submucosa of the gastrointestinal tract.
In the body, toltrazuril is metabolized by sulfoxidation and hydroxylation to form sulfoxide and sulfone.
It is eliminated from the body mainly unchanged – up to 70%, and as metabolites in the faeces and partially in the urine.
How to use and dosage :
Toltrazuril is administered to calves, lambs, goats, piglets, rabbits, dog puppies and fur-bearing animals for treatment and prophylaxis of coccidiosis.
Table
Kind of animal | Age | Dose of medicinal product per 1 kg of animal weight | Frequency rate and duration of drug use | |
DV, mg / kg | suspension, ml / kg | |||
Calves, lambs and kids | from 14 days | 15 | 0.3 | once |
Piglets | from 3 days | twenty | 0.4 (not less than 0.5 and not more than 2 ml / animal) | once |
Dog puppies | from 14 days | ten | 0.2 | Once a day, 3 consecutive days |
Toltrazuril is administered to animals orally individually using a dosing syringe or mixed with a small amount of feed.
In case of sedimentation the container with suspension shall be shaken thoroughly before use.
No peculiarities of the drug action during its first use and withdrawal were revealed.
Pregnant females, if necessary, the drug shall be used after consultation with a veterinarian in the second half of pregnancy. The drug is not intended for use in milking animals.
Violation of the scheme of drug administration shall be avoided as it may lead to reduction of its effectiveness. In case of missing the next dose the drug shall be administered as soon as possible in the same dose, further the interval between injections of the drug shall not be changed.
Slaughter of calves, lambs, goats and rabbits for meat shall be allowed not earlier than 63 days, piglets – not earlier than 70 days after administration.
Storage :
Store the drug in the manufacturer’s sealed container, protected from direct sunlight, away from food and feed at 32-77F (0°C to 25°C).
Shelf life of the drug is – 3 years from the date of production
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